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Abeprazan hydrochloride

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SL-9453

Abeprazan hydrochloride, >98%

CAS No. : [1902954-87-3]

Synonyms : Fexuprazan hydrochloride; DWP-14012 hydrochloride

IUPAC Name : 1-(5-(2,4-Difluorophenyl)-1-((3-fluorophenyl)sulfonyl)-4-methoxy-1H-pyrrol-3-yl)-N-methylmethanamine hydrochloride

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Chemical Properites
Mol. Formula :
C19H17F3N2O3S • HCl
Mol. Weight :
446.87
Appearance :
Pale brown solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : Abeprazan hydrochloride is a potassium-competitive acid blocker that inhibits H+, K+-ATPase by reversible potassium-competitive ionic binding, without requiring acid activation. It is being developed as an alternative to proton pump inhibitors for the treatment of acid-related diseases.

References : Sunwoo J. et al.: Aliment Pharmacol Ther., 48(2), 206-218, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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