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Abiraterone methyl ether

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Abiraterone methyl ether, >98%

CAS No. : [1470276-23-3]

IUPAC Name : 3-((3S,8R,9S,10R,13S,14S)-3-Methoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C25H33NO
Mol. Weight :
363.54
Appearance :
White solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : Abiraterone methyl ether is an impurity of Abiraterone, which is a potent, selective, and irreversible CYP17 inhibitor, is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.

References : Attard G. et al.: J. Clin. Oncol. 26(28), 4563-4571. 2008; Richards J. et al.: Cancer Res. 72(9), 2176-2182, 2012; Stein M. N. et al.: Asian J. Androl. 16(3), 387-400, 2014; Li R. et al.: Clin Cancer Res. 18(13), 3571-3579, 2012; Kumar S. V. et al. V. Biomed Chromatogr., 27(2), 203-207, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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