Acalabrutinib nitroso impurity 1 (mixture of isomers)

SL-7844

Acalabrutinib nitroso impurity 1 (mixture of isomers), >98%

Synonyms : N-Nitroso acalabrutinib impurity 1

IUPAC Name : (S)-4-(8-Amino-3-(1-nitrosopyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
10MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
100MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : This is a nitrosamine impurity of Acalabrutinib, which is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor. Acalabrutinib is used to treat a type of non-Hodgkin lymphoma known as mantle cell lymphoma.

References : Wu J. et al.: J. Hematol Oncol., 9, 21, 2016; Heather L. G. et al.: Cancer Res., 74(19 Supplement), 1744, 2014; Todd C. et al. Cancer Res., 75(15 Supplement), 25, 2015; Qin J. et al.: J. Immun., 43, 107-120, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.