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Acetazolamide-d3 EP impurity A

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SL-6297

Acetazolamide-d3 EP impurity A, >98% (HPLC)

Isotopic Purity : 99 atom % D

IUPAC Name : N-(5-Chloro-1,3,4-thiadiazol-2-yl)acetamide-d3

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Chemical Properites
Mol. Formula :
C4HD3ClN3OS
Mol. Weight :
180.62
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version an impurity of Acetazolamide (Acetazolamide-d3 EP impurity A). Acetazolamide is a potent carbonic anhydrase (CA) inhibitor, which is commonly used in clinical practice as an immediate and readily available option for acute reduction of intraocular pressure (IOP).

References : Radhakrishnan R. et al.: J. Pharmacol Exp Ther., 313(2), 921-927, 2005; Xiang Y. et al.: Acta Pharmacol Sin., 25(6), 812-816, 2004; Parkkila S. et al.: Proc Natl Acad Sci U S A. 97(5), 2220-2224, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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