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Acetazolamide-d6 EP impurity F

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SL-6307

Acetazolamide-d6 EP impurity F, >98% (HPLC)

Isotopic Purity : 99 atom % C

Synonyms : Bis-[5-(acetylamino)-1,3,4-thiadiazole-2-sulfonyl]amine-d6

IUPAC Name : N,N'-[Iminobis(sulfonyl-1,3,4-thiadiazole-5,2-diyl)]bisacetamide-d6

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Chemical Properites
Mol. Formula :
C8H3D6N7O6S4
Mol. Weight :
433.48
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version an impurity of Acetazolamide (Acetazolamide-d3 EP impurity F). Acetazolamide is a potent carbonic anhydrase (CA) inhibitor, which is commonly used in clinical practice as an immediate and readily available option for acute reduction of intraocular pressure (IOP).

References : Radhakrishnan R. et al.: J. Pharmacol Exp Ther., 313(2), 921-927, 2005; Xiang Y. et al.: Acta Pharmacol Sin., 25(6), 812-816, 2004; Parkkila S. et al.: Proc Natl Acad Sci U S A. 97(5), 2220-2224, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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