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ACH-000143

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SI-6168

ACH-000143, >98% (HPLC)

CAS No. : [2225836-30-4]

IUPAC Name : N-(2-(5-Chloro-2,6-dimethoxy-1H-benzo[d]imidazol-1-yl)ethyl)acetamide

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Chemical Properites
Mol. Formula :
C13H16ClN3O3
Mol. Weight :
297.74
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : ACH‑000143 is an orally active melatonin receptor agonist with exceptional potency at MT1 (EC50 = 0.06 nM) and MT2 (EC50 = 0.32 nM). Its high melatonergic activity supports its use in studies of circadian regulation, sleep biology, and MT‑receptor pharmacology.

References : Antonio F. M. Jr. et al.: J. Med. Chem., 64(4), 1904-1929, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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