AChE inhibitor

SI-6122

AChE inhibitor, >98% (HPLC)

IUPAC Name : 2-((4-Fluoro-1-(2-fluorobenzyl)piperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This is a high‑potency, selective, orally bioavailable AChE inhibitor with long target‑residence time, brain‑preferential distribution, and superior cognitive efficacy to donepezil in mouse AD models. Phase I data show good safety, tolerability, and PK, supporting advancement to phase II for Alzheimer’s disease.

References : Zhou Y. et al.: J. Med. Chem., 64(4), 1844-1855, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.