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Acotiamide-d6

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Acotiamide-d6, >99% (HPLC)

Isotopic Purity : 99 atom % D

Related CAS No. : [185106-16-5] of the unlabelled compound

Synonyms : N-[2-[Bis(1-methylethyl)amino]ethyl]-2-[((2-hydroxy-4,5-dimethoxy-d6)- benzoyl)amino]-4-thiazolecarboxamide; Z 388-d6; YM 443-d6

IUPAC Name : N-(2-(Diisopropylamino)ethyl)-2-(2-hydroxy-4,5-bis(methoxy-d3)benzamido)thiazole-4-carboxamide

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Chemical Properites
Mol. Formula :
C21H24D6N4O5S
Mol. Weight :
456.59
Appearance :
White to Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Acotiamide-d6 is is a deuterium labelled version an analog of Acotiamide, which is an acetylcholinesterase inhibitor. It has been shown to stimulate gastric motility and improve gastric motility dysfunction in rats (1,2). It has also been shown to improve meal-related symptoms of functional dyspepsia.

References : Masanao K. et. al.: Eur. J. Pharmacol., 666, 218,2011; Matsunaga Y. et. al.: J. Pharmacol. Exp. Ther., 336, 791,2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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