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ACP-5862-d4 (pyridine-d4)

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SL-7095

ACP-5862-d4 (pyridine-d4), >98%

Isotopic Purity : 98 atom % D

IUPAC Name : 4-(8-Amino-3-(4-(but-2-ynamido)butanoyl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl-d4)benzamide

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
10MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C26H19D4N7O3
Mol. Weight :
485.54
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version metabolite of Acalabrutinib, which is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor. It is used to treat a type of non-Hodgkin lymphoma known as mantle cell lymphoma.

References : Wu J. et al.: J. Hematol Oncol., 9, 21, 2016; Heather L. G. et al.: Cancer Res., 74(19 Supplement), 1744, 2014; Todd C. et al. Cancer Res., 75(15 Supplement), 25, 2015; Qin J. et al.: J. Immun., 43, 107-120, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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