ACT-335827

SI-7569

ACT-335827, >98% (HPLC)

CAS No. : [1354039-86-3]

IUPAC Name : (R)-2-((S)-1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-N-isopropyl-2-phenylacetamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : ACT‑335827 selectively blocks OX1R with nanomolar potency while sparing OX2R. Its oral activity and brain penetration make it a valuable tool for probing orexin‑dependent mechanisms relevant to neurological disease models.

References : Steiner A. M. et al.: Chem. Med. Chem., 8(6), 898-903, 2013; Steiner A. M. et al.: Front. Pharmacol., 4, 165, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.