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ACT-660602

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SI-7151

ACT-660602, >98% (HPLC)

CAS No. : [1646267-59-5]

IUPAC Name : (R)-2-(3,5-Dimethyl-1H-1,2,4-triazol-1-yl)-1-(2-methyl-4-(2-(trifluoromethyl)-4-(2-(trifluoromethyl)pyrimidin-5-yl)thiazol-5-yl)piperazin-1-yl)ethan-1-one

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Chemical Properites
Mol. Formula :
C20H20F6N8OS
Mol. Weight :
534.49
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : ACT‑660602 potently antagonizes CXCR3 (IC50 = 204 nM), inhibits T‑cell migration, and demonstrates efficacy in acute lung injury models. It is well suited for studies of autoimmune and inflammatory disorders.

References : Meyer E. A. et al.: J. Med. Chem., 65(17), 11513-11532, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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