ACT-777991

SI-7292

ACT-777991, >98% (HPLC)

CAS No. : [1967811-46-6]

IUPAC Name : (R)-1-(2-(2-Hydroxyethyl)-4-(2-(trifluoromethyl)-4-(2-(trifluoromethyl)pyrimidin-5-yl)thiazol-5-yl)piperazin-1-yl)-2-(3-methyl-1H-1,2,4-triazol-1-yl)ethan-1-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : ACT‑777991 selectively targets CXCR3 and maintains metabolic stability across species in both microsomal and hepatocyte assays. It effectively inhibits activated T‑cell chemotaxis toward CXCL11, making it a valuable tool for investigating CXCR3‑dependent inflammatory pathways.

References : Meyer E. A. et al.: J. Med. Chem., 66(6), 4179-4196, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.