ADAMTS‑5 inhibitor

SI-6236

ADAMTS‑5 inhibitor, >98% (HPLC)

IUPAC Name : N-((1-(4-(((1-Methyl-1H-imidazol-2-yl)methyl)amino)-6-(propylamino)-1,3,5-triazin-2-yl)pyrrolidin-2-yl)methyl)-4-propylbenzenesulfonamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This is a potent and highly selective ADAMTS‑5 inhibitor discovered using encoded library technology (ELT), notable for lacking a classical zinc‑binding group. It inhibits ADAMTS‑5 with IC₅₀ = 30 nM, showing >50‑fold selectivity over ADAMTS‑4 and >1000‑fold selectivity over ADAMTS‑1, ADAMTS‑13, MMP‑13, and TACE.

References : Deng H. et al.: J. Med. Chem., 55(16), 7061−7079, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.