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ADAMTS inhibitor C7

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SI-6237

ADAMTS inhibitor C7, >98% (HPLC)

CAS No. : [1607004-34-1]

Synonyms : ADAMTS-4/5-IN-1

IUPAC Name : (S)-2-Cyclopropyl-N-(((R)-4-cyclopropyl-2,5-dioxoimidazolidin-4-yl)methyl)-3-(4-(trifluoromethyl)phenyl)propanamide

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Back Order  Estimated to ship on 04 October 2026
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250MGRequest A Quote
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C20H22F3N3O3
Mol. Weight :
409.41
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : ADAMTS‑4/5‑IN‑1 potently inhibits the aggrecanases ADAMTS‑4 and ADAMTS‑5 (IC50 = 2 nM each) with minimal activity on MMPs. By lowering aggrecan‑degradation products in synovial fluid, it provides a robust pharmacological tool for probing cartilage‑catabolic pathways in osteoarthritis models.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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