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Adavivint

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SI-7600

Adavivint, >98% (HPLC)

CAS No. : [1467093-03-3]

Synonyms : Lorecivivint; SM-04690

IUPAC Name : N-(5-(3-(7-(3-Fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl)-1H-indazol-5-yl)pyridin-3-yl)-3-methylbutanamide

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C29H24FN7O
Mol. Weight :
506.56
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Adavivint selectively inhibits canonical Wnt signaling with an EC50 of 19.5 nM in TCF/LEF reporter assays using SW480 cells. Its potency and pathway specificity support its use in studies of Wnt‑dependent cancer biology.

References : Deshmukh V. et al.: Osteoarthritis Cartilage, 26(1), 18-27, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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