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Adefovir dipivoxil N6-hydroxy methyl impurity

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Adefovir dipivoxil N6-hydroxy methyl impurity, >96%

CAS No. : [323201-04-3]

IUPAC Name : ((((2-(6-((Hydroxymethyl)amino)-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)

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Chemical Properites
Mol. Formula :
C21H34N5O9P
Mol. Weight :
531.50
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Adefovir dipivoxil, which is a reverse transcriptase inhibitor. It is used in the treatment of chronic hepatitis B virus (HBV).

References : Julander J. G. et al.: Antiviral Res., 55(1), 27-40, 2002; Delmas J. et al.: Antimicrob Agents Chemother., 46(2), 425-433, 2002; Delaney W. E 4th, et al.: Antimicrob Agents Chemother., 48(10), 3702-3710, 2004; Ying. et al.: J. Viral Hepat., 7(1), 79-83, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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