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SI-6855

Admilparant, >98% (HPLC)

CAS No. : [2170126-74-4]

Synonyms : BMS-986278

IUPAC Name : (1S,3S)-3-((2-Methyl-6-(1-methyl-5-(((methyl(propyl)carbamoyl)oxy)methyl)-1H-1,2,3-triazol-4-yl)pyridin-3-yl)oxy)cyclohexane-1-carboxylic acid

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C22H31N5O5
Mol. Weight :
445.52
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BMS‑986278 selectively inhibits LPA₁ with nanomolar potency (Kᵦ = 6.9 nM human; 4.0 nM mouse) and demonstrates oral activity. It is a valuable tool for investigating LPA₁‑driven pathways in pulmonary fibrosis and other fibrotic disease models.

References : Cheng P. T. W. et, al.: J. Med. Chem., 64(21), 15549-15581, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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