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Isotopic Purity : 99 atom % D
CAS No. : [1313874-96-2]
MDL No. : MFCD30747909
Synonyms : BIBW 2992-d6
IUPAC Name : (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethyl-d3-amino)but-2-enamide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 10MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 25MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C24H19D6ClFN5O3 | Mol. Weight : 491.98 |
Appearance : White to Off-white solid | Melting Point : Not available |
Solubility : DMSO | |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Afatinib-d6 is a deuterium labelled version of Afatinib, which is an irreversible EGFR family inhibitor for the treatment of cancer.
References : Li D. et al.: Oncogene. 27(34), 4702-4711, 2008; Perera S. A. et al. Proc Natl Acad Sci U S A. 106(2), 474-479, 2009; Takezawa K. et al.: Mol Cancer Ther., 9(6),1647-1656, 2010.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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