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Afatinib-d6

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Afatinib-d6, >99% (HPLC)

Isotopic Purity : 99 atom % D

CAS No. : [1313874-96-2]

MDL No. : MFCD30747909

Synonyms : BIBW 2992-d6

IUPAC Name : (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethyl-d3-amino)but-2-enamide

Price And Availability
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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
10MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C24H19D6ClFN5O3
Mol. Weight :
491.98
Appearance :
White to Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Afatinib-d6 is a deuterium labelled version of Afatinib, which is an irreversible EGFR family inhibitor for the treatment of cancer.

References : Li D. et al.: Oncogene. 27(34), 4702-4711, 2008; Perera S. A. et al. Proc Natl Acad Sci U S A. 106(2), 474-479, 2009; Takezawa K. et al.: Mol Cancer Ther., 9(6),1647-1656, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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