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Afatinib impurity 2

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SL-7136

Afatinib impurity 2, >98%

CAS No. : [1449430-45-8]

IUPAC Name : 4-((3-Chloro-4-fluorophenyl)amino)-6-nitroquinazolin-7-ol

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C14H8ClFN4O3
Mol. Weight :
334.69
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Afatinib (Afatinib impurity 2), which is an irreversible EGFR family inhibitor. It is used to treat metastatic non-small cell lung cancer (NSCLC).

References : Li D. et al.: Oncogene 27(34), 4702-4711, 2008; Ferrarotto R. et al.: Expert Opin Investig Drugs 23(1), 135-43, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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