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Afatinib impurity B
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SI-3914
Afatinib impurity B, >98%
CAS No. : [314771-76-1]
MDL No. : MFCD18642925
IUPAC Name : (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 1G | 15.00 | Back Order | Estimated to ship on 20 September 2026 | |
| 5G | 60.00 | Back Order | Estimated to ship on 20 September 2026 | |
| 10G | 115.00 | Back Order | Estimated to ship on 20 September 2026 | |
| 25G | 225.00 | Back Order | Estimated to ship on 20 September 2026 | |
| 100G | 795.00 | Back Order | Estimated to ship on 20 September 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C18H16ClFN4O2 | Mol. Weight : 374.80 |
Appearance : Pale yellow solid | Melting Point : Not available |
Solubility : DMSO | |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : This is an impurity of Afatinib, which is an irreversible EGFR family inhibitor, used to treat metastatic non-small cell lung cancer (NSCLC).
References : Ding X. H. et al.: Bioorg. Med. Chem. 23(9), 1895-1922, 2015.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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