Aficamten

SI-6786

Aficamten, >98% (HPLC)

CAS No. : [2364554-48-1]

Synonyms : CK-3773274; CK-274

IUPAC Name : (R)-N-(5-(5-Ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)-1-methyl-1H-pyrazole-4-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Aficamten selectively inhibits cardiac myosin with micromolar potency (IC₅₀ = 1.4 µM), making it a valuable tool for investigating sarcomere function and therapeutic strategies for hypertrophic cardiomyopathy.

References : Chihyuan Chuang. et al.: J. Med. Chem., 64(19), 14142-14152, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.