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Aficamten-d3

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SI-6787

Aficamten-d3, >98% (HPLC)

Synonyms : CK-3773274-d3; CK-274-d3

IUPAC Name : (R)-N-(5-(5-Ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)-1-(methyl-d3)-1H-pyrazole-4-carboxamide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
10MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C18H16D3N5O2
Mol. Weight :
340.4
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Aficamten‑d₃ is a deuterium‑labelled version of Aficamten. This labelled analog is valuable for pharmacokinetic, metabolic, and mechanistic investigations related to hypertrophic cardiomyopathy. Aficamten inhibits cardiac myosin.

References : Russak E. M. et al.: Ann. Pharmacother., 53(2), 211-216, 2019; Chihyuan Chuang et al.: J. Med. Chem., 64(19), 14142-14152, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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