AG-1478-d6

SI-5163

AG-1478-d₆, >98% (HPLC)

Isotopic Purity : 98 atom % D

Related CAS No. : [153436-53-4] of the unlabelled compound

Synonyms : Tyrphostin AG-1478-d₆ ; NSC 693255-d₆

IUPAC Name : 6,7-Dimethoxy-d₆-4-(3'-chloroanilino)quinazoline;

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5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
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Applications : This is the deuterium labelled analog of AG-1478. A selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG-1478 hydrochloride has antiviral effects against HCV and encephalomyocarditis virus (EMCV).

References : Jo M. et. al.: J. Bio. Chem., 275(12), 8806, 2000; Bojko A. et al.: Folia Histochem Cytobiol., 50(2), 186-195, 2012; Li W. et al.: Sci Rep., 6, 24580, 2016; Akhtar S. et al.: PLoS One 10(7), e0132215, 2015; Dorobantu C. M. et al.: Antimicrob Agents Chemother., 60(10), 6402-6, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.