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Isotopic Purity : 99 atom % D
MDL No. : MFCD28386061
Related CAS No. : [170449-18-0] of the unlabelled compound
Synonyms : Tyrphostin AG-1478-d6 hydrochloride; NSC-693255-d6 hydrochloride
IUPAC Name : 6,7-Dimethoxy-d6-4-(3'-chloroanilino)quinazoline hydrochloride
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 10MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 25MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C16H8D6ClN3O2 . HCl | Mol. Weight : 358.25 |
Appearance : Off-white solid | Melting Point : 258-260oC |
Solubility : DMSO | |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : This is a deuterium labelled analog of AG-1478 hydrochloride. A selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG-1478 hydrochloride has antiviral effects against HCV and encephalomyocarditis virus (EMCV).
References : Jo M. et. al.: J. Bio. Chem., 275(12), 8806, 2000; Bojko A. et al.: Folia Histochem Cytobiol., 50(2), 186-195, 2012; Li W. et al.: Sci Rep., 6, 24580, 2016; Akhtar S. et al.: PLoS One 10(7), e0132215, 2015; Dorobantu C. M. et al.: Antimicrob Agents Chemother., 60(10), 6402-6, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term storage.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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