AG-270

SI-7133

AG-270, >98% (HPLC)

CAS No. : [2201056-66-6]

IUPAC Name : 3-(Cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-phenyl-5-(pyridin-2-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : AG‑270 is an orally active, reversible allosteric inhibitor of MAT2A with strong potency (IC₅₀ = 14 nM). As a first‑in‑class compound, it is well suited for probing MAT2A‑regulated metabolic pathways in cancer.

References : Zenon K. et al.: J. Med. Chem., 64(8), 4430-4449, 2021

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.