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Agerafenib

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SI-6032

Agerafenib, >98% (HPLC)

CAS No. : [1188910-76-0]

MDL No. : MFCD22124524

Synonyms : CEP-32496; RXDX-105

IUPAC Name : 1-(3-((6,7-Dimethoxyquinazolin-4-yl)oxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea

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Chemical Properites
Mol. Formula :
C24H22F3N5O5
Mol. Weight :
517.47
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Agerafenib is a highly potent and orally efficacious inhibitor of BRAF(V600E).

References : Rowbottom W. M. et al.: J Med Chem., 55(3), 1082-105, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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