AGI-6780

SI-7372

AGI-6780, >98% (HPLC)

CAS No. : [1432660-47-3]

IUPAC Name : N-Cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : AGI‑6780 selectively targets the tumor‑associated IDH2^R140Q mutant with low‑nanomolar potency (IC₅₀ = 23 ± 1.7 nM) and displays significantly weaker inhibition of IDH2^WT (IC₅₀= 190 ± 8.1 nM). This differential activity profile highlights its value as a tool compound for dissecting mutant IDH2‑driven metabolic reprogramming.

References : Wang F. et al.: Science, 340(6132), 622-6, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.