ALE-0540

SI-7691

ALE-0540, >98% (HPLC)

CAS No. : [234779-34-1]

IUPAC Name : 2-((2-Hydroxyethyl)amino)-5-nitro-1H-benzo[de]isoquinoline-1,3(2H)-dione

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : ALE‑0540 is a small‑molecule NGF antagonist that interferes with NGF binding to TrkA and to the p75/TrkA receptor complex, with IC₅₀ values of 5.88 µM and 3.72 µM. Its ability to modulate NGF‑mediated signaling makes it useful for probing molecular mechanisms underlying pain processing.

References : Owolabi J. B. et al.: J. Pharmacol. Exp. Ther., 289(3), 1271-6, 1999.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.