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Alisertib-d3

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SI-4901

Alisertib-d3, >98% (HPLC)

Isotopic Purity : 99 atom % D

Synonyms : MLN-8237-d3; MLN-8237-d3

IUPAC Name : 4-((9-Chloro-7-(2-fluoro-(6-methoxy-d3)-phenyl)-5H-benzo[c]pyrimido[4,5-e]azepin-2-yl)amino)-2-methoxybenzoic acid

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
10MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C27H17D3ClFN4O4
Mol. Weight :
521.94
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Alisertib-d3 is a deuterium labelled version an analog of Alisertib, which is an orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase aurora A kinase (AAK) with potential antineoplastic activity.

References : Manfredi M. G. et al.: Clin Cancer Res.,17(24), 7614-7624, 2011; Gorgun G. et al.: Blood, 115(25), 5202-521, 2010; Sehdev V. et al. Mol Cancer Ther., 11(3), 763-774, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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