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CAS No. : [2134096-06-1]
Synonyms : HS-10296 mesylate
IUPAC Name : N-(5-((4-(1-Cyclopropyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide methanesulfonate
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C30H35N7O2 • CH3SO2OH | Mol. Weight : 621.76 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Almonertinib mesylate is an irreversible, orally active third‑generation EGFR inhibitor that selectively targets EGFR‑sensitizing mutations and the T790M resistance mutation. It shows sub‑nanomolar potency against T790M, T790M/L858R, and T790M/Del19 variants and reduced activity toward wild‑type EGFR, supporting its use in NSCLC research.
References : Yang H. C. J. et al.: J. Thorac. Oncol., 15(12), 1907-1918, 2020; Sullivan I. et al.: Front Med (Lausanne), 3, 76, 2017.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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