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Alobresib

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SI-5987

Alobresib, >98% (HPLC)

CAS No. : [1637771-14-2]

IUPAC Name : (2-Cyclopropyl-5-(3,5-dimethylisoxazol-4-yl)-1H-benzo[d]imidazol-7-yl)diphenylmethanol

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Chemical Properites
Mol. Formula :
C28H25N3O2
Mol. Weight :
435.53
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Alobresib is a BET bromodomain inhibitor. A highly effective therapeutics agent against recurrent/chemotherapy resistant uterine serous carcinoma (USC) overexpressing c-Myc.

References : Bonazzoli E. et al.: Clin Cancer Res., 24(19), 4845-4853, 2018; Kim E. et al.: Leukemia 34(6), 1588-1598, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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