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Alogliptin benzoate

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SI-2861

Alogliptin benzoate, >98% (HPLC)

CAS No. : [850649-62-6]

MDL No. : MFCD09833195

Synonyms : SYR-322

IUPAC Name : (R)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile benzoate

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Chemical Properites
Mol. Formula :
C19H21N5O2 . C7H6O2
Mol. Weight :
461.52
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Alogliptin benzoate is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.

References : K. K-C. Liu et al.: Bioorg. Med. Chem. 20(3), 1155-1174, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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