Alpelisib hydrochloride

SI-5321

Alpelisib hydrochloride, >98% (HPLC)

CAS No. : [1584128-91-5]

Synonyms : BYL-719 hydrochloride

IUPAC Name : (S)-N1-(4-Methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-yl)pyrrolidine-1,2-dicarboxamide hydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Alpelisib hydrochloride is a potent and selective PI3Kα inhibitor with IC50 of 5 nM in a cell-free assay, and minimal effect on PI3Kβ/γ/δ. Alpelisib hydrochloride is used with combination of Fulvestrant to treat certain types of breast cancer.

References : Furet P. et al.: Bioorg Med Chem Lett., 23(13), 3741-3748, 2013; Fritsch C. et al.: Mol Cancer Ther., 13(5), 1117-1129, 2014; Gobin B. et al.: Int. J. Cancer 136(4), 784-796, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.