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Alverine hydrochloride

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SL-9219

Alverine hydrochloride, >98%

CAS No. : [5982-87-6]

IUPAC Name : N-Ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine hydrochloride

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Chemical Properites
Mol. Formula :
C20H27N • HCl
Mol. Weight :
317.90
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Alverine hydrochloride is a 5-HT1A receptor antagonist, with an IC50 of 101 nM. It is used to treat muscle spasms and related pain in the stomach and intestines, primarily for Irritable Bowel Syndrome (IBS) and diverticular disease.

References : Coelho A. M. et al.: J. Pharm Pharmacol., 53(10), 1419-26, 2001; Hayase M. et al.: Br. J. Pharmacol., 152(8), 1228-38, 2007.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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