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Alvimopan acyl β-D-glucuronide

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SL-5488

Alvimopan acyl β-D-glucuronide, >98%

CAS No. : [1260616-95-2]

Synonyms : Alvimopan acyl glucuronide

IUPAC Name : (2R,3R,4R,5S,6R)-6-((((S)-2-Benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoyl)glycyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

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Chemical Properites
Mol. Formula :
C31H40N2O10
Mol. Weight :
600.67
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a glucuronide metabolite of Alvimopan, which is a potent, relatively nonselective opioid antagonist, used to avoid postoperative ileus following small or large bowel resection and accelerates the gastrointestinal recovery period.

References : Bourdonnec B. L. et al.: Bioorg Med Chem Lett.,18(6), 2006-2012, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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