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AM-8123

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SI-6242

AM-8123, >98% (HPLC)

CAS No. : [2049973-02-4]

IUPAC Name : (1S,2S)-N-(4-(2,6-Dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-1-isopropoxy-1-(5-methylpyrimidin-2-yl)propane-2-sulfonamide

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C27H33N7O5S
Mol. Weight :
567.67
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : AM‑8123 is an oral APJ agonist that reduces forskolin‑stimulated cAMP levels and drives Gα‑protein activation. Its pharmacological profile supports its use in probing apelin/APJ signaling mechanisms relevant to cardiovascular physiology and disease.

References : Ason B. et al.: JCI Insight., 5(8), e132898, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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