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AM-9514

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SI-7727

AM-9514, >98% (HPLC)

CAS No. : [1442677-18-0]

IUPAC Name : 1-(3-((1-Ethyl-1H-pyrazol-5-yl)oxy)-5-(((1r,3s)-3-hydroxy-3-methylcyclobutyl)methyl)pyridin-2-yl)-3-methylurea

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Chemical Properites
Mol. Formula :
C18H25N5O3
Mol. Weight :
359.43
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : AM‑9514 activates glucokinase with high potency (EC50= 0.29 µM), making it a valuable tool compound for probing GK‑dependent pathways and glucose homeostasis.

References : Du X. et al.: ACS Med. Chem. Lett., 5(12), 1284-9, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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