Ambrisentan vinyloxy impurity

SL-5008

Ambrisentan vinyloxy impurity, >98%

CAS No. : [1639429-81-4]

IUPAC Name : 2-((2,2-Diphenylvinyl)oxy)-4,6-dimethylpyrimidine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	225.00		In Stock	Estimated to ship on 20 September 2026
50MG	425.00		In Stock	Estimated to ship on 20 September 2026
100MG	825.00		In Stock	Estimated to ship on 20 September 2026
250MG	1695.00		In Stock	Estimated to ship on 20 September 2026
500MG	2995.00		In Stock	Estimated to ship on 20 September 2026
1G	3995.00		In Stock	Estimated to ship on 20 September 2026

Applications : This is an impurity of Ambrisentan, which is a highly selective antagonist of the endothelin-1 type A receptor (ETAR), used in the treatment of pulmonary arterial hypertension (PAH).

References : Weiss J. et al.: Eur J Pharmacol, 660(2-3), 298-304, 2011; Yokoyama Y. et al.: Biol Pharm Bull, 37(3), 461-465, 2014; Weiss J. et al.: Biochem Pharmacol, 85(2), 265-273, 2013; Osano A. et al.: J. Pharmacol Sci, 124(1), 86-91, 2014; Buckley M. S. et al.: Expert Opin Drug Metab Toxicol, 7(3), 371-380, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.