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Ambroxol

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SL-10141

Ambroxol, >98%

CAS No. : [18683-91-5]

Synonyms : NA-872

IUPAC Name : (1r,4r)-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexan-1-ol

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Chemical Properites
Mol. Formula :
C13H18Br2N2O
Mol. Weight :
378.11
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Ambroxol is an active metabolite of the prodrug Bromhexine, exhibits significant expectorant properties. It acts as a glucocerebrosidase (GCase) chaperone, enhancing GCase activity. Additionally, Ambroxol induces pulmonary autophagy and shows potential in research related to Parkinson’s disease and neuronopathic Gaucher disease.

References : Deretic V. et al.: Expert Opin Drug Metab Toxicol., 15(3), 213-218, 2019; Migdalska-Richards A. et al.: Ann Neurol., 80(5), 766-775, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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