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AMG-131 benzenesulfonate

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SI-6625

AMG-131 benzenesulfonate, >98% (HPLC)

CAS No. : [849738-78-9]

Synonyms : INT-131 benzenesulfonate

IUPAC Name : 2,4-Dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide benzenesulfonate

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C21H12Cl4N2O3S • C6H5SO2OH
Mol. Weight :
672.37
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : AMG-131 benzenesulfonate selectively modulates PPARγ through a non‑TZD scaffold. It binds in the TZD pocket but occupies a unique region and contacts different residues than classical TZDs, giving rise to a distinct SPPARM activity profile. It is widely used in type‑2 diabetes research.

References : Linda S. Higgins et al.: PPAR Res., 2008, 936906, 2008; Alykhan Motani et al.: J. Mol. Biol., 386(5), 1301-11, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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