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AMG-333

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SI-1054

AMG-333, >98% (HPLC)

CAS No. : [1416799-28-4]

IUPAC Name : (S)-6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic acid

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Chemical Properites
Mol. Formula :
C20H12F5N3O4
Mol. Weight :
453.32
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : A novel potent, highly selective TRPM8 antagonist with IC50 of 13 nM and 20 nM for hTRPM8 and rTRPM8, respectively.

References : Horne B. D. et al.: J. Med. Chem., 61(18), 8186-8201, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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