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CAS No. : [1401034-19-2]
Synonyms : FLX-925 hydrochloride
IUPAC Name : 2-Hydroxy-1-(2-((9-((1r,4r)-4-methylcyclohexyl)-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl)amino)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)ethan-1-one hydrochloride
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C26H29N7O2 • HCl | Mol. Weight : 508.02 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : AMG-925 HCl inhibits FLT3 and CDK4 with low‑nanomolar potency (IC50= 2 ± 1 nM and 3 ± 1 nM), providing a dual‑targeted tool for probing proliferative and FLT3‑mediated oncogenic pathways.
References : Keegan K. et al.: Mol. Cancer Ther., 13(4), 880-9, 2014.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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