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Aminoalcohol bis(ethoxycarbonyl) efavirenz

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Aminoalcohol bis(ethoxycarbonyl) efavirenz, >98%

CAS No. : [2733280-20-9]

IUPAC Name : Ethyl (S)-(4-chloro-2-(4-cyclopropyl-2-((ethoxycarbonyl)oxy)-1,1,1-trifluorobut-3-yn-2-yl)phenyl)carbamate

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Chemical Properites
Mol. Formula :
C19H19ClF3NO5
Mol. Weight :
433.81
Appearance :
Solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Efavirenz, which is a synthetic non-nucleoside reverse transcriptase (RT) inhibitor, an antiretroviral drug used to treat and prevent HIV/AIDS.

References : Braz V. A. et al.: Biochemistry, 49(3), 601-10, 2010; Funes H. A. et al.: J. Antimicrob Chemother., 70(8), 2249-54, 2015; Apostolova N. et al.: J. Hepatol., 59(4), 780-9, 2013; Caulk A. W. et al.: J. Biomech., 48(10), 2176-80, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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