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Amitriptyline N-beta-D-glucuronide

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SI-7681

Amitriptyline N-β-D-glucuronide, >98% (HPLC)

CAS No. : [112806-33-4]

IUPAC Name : (2R,3R,4R,5S,6S)-6-((3-(10,11-Dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)propyl)dimethylammonio)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate

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Chemical Properites
Mol. Formula :
C26H31NO6
Mol. Weight :
453.54
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Amitriptyline N‑β‑D‑glucuronide is a glucuronide conjugate generated through phase II metabolism of Amitriptyline. As an ammonium glucuronide, it is excreted in urine and serves as a characteristic metabolic marker of Amitriptyline disposition.

References : Iddon L. et al.: Tetrahedron, 66(2), 537–541, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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