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Amlodipine impurity

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Amlodipine impurity, >98%

IUPAC Name : (2-((4-(2-Chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridin-2-yl)methoxy)ethyl)glycine hydrochloride

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Chemical Properites
Mol. Formula :
C22H27ClN2O7 • HCl
Mol. Weight :
503.37
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Amlodipine, which is a long-acting calcium channel blocker. Amlodipine is used alone or together with other medicines to treat hypertension.

References : Arrowsmith J. E. et al.: J. Med. Chem., 29, 1696, 1986; Burges R. A. et al.: J. Cardiovasc. Pharmacol., 9, 110, 1987; Haria M. et al.: Drugs, 50, 560, 1995.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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