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Amprenavir

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SI-5890

Amprenavir, >98% (HPLC)

CAS No. : [161814-49-9]

MDL No. : MFCD00934214

Synonyms : VX-478

IUPAC Name : (S)-Tetrahydrofuran-3-yl ((2S,3R)-4-((4-amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate

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Chemical Properites
Mol. Formula :
C25H35N3O6S
Mol. Weight :
505.63
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Amprenavir is a HIV protease inhibitor, used to treat HIV infection. Amprenavir is also a SARS-CoV 3CLpro inhibitor for the potential treatment of COVID-19.

References : Sadler B. M. et al.: Ann Pharmacother., 36(1), 102-18, 2002; Esposito V. et al.: J. Cell Physiol., 228(3), 640-5, 2013. Helsley R. N. et al.: Mol Pharmacol., 83(6), 1190-9, 2013; Qi Sun et al.: Signal Transduct Target Ther., 6(1), 212, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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