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Apalutamide

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SL-7535

Apalutamide, >98% (HPLC)

CAS No. : [956104-40-8]

MDL No. : MFCD22380626

Synonyms : ARN-509

IUPAC Name : 4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-methylbenzamide

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Chemical Properites
Mol. Formula :
C21H15F4N5O2S
Mol. Weight :
477.44
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Apalutamide is a selective and competitive androgen receptor inhibitor with IC50 of 16 nM in a cell-free assay, useful for prostate cancer treatment.

References : Clegg N. J. et al.: Cancer Res., 72(6), 1494-1503, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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