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Apalutamide ethyl ester

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Apalutamide ethyl ester, >98%

CAS No. : [1332388-83-6]

Synonyms : Apalutamide impurity J

IUPAC Name : Ethyl 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate

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Chemical Properites
Mol. Formula :
C22H16F4N4O3S
Mol. Weight :
492.45
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an analog or impurity of Apalutamide, which is a selective and competitive androgen receptor inhibitor. Apalutamide is used in the treatment of prostate cancer.

References : Clegg N. J. et al.: Cancer Res., 72(6), 1494-1503, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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