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Apararenone

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SI-6116

Apararenone, >98% (HPLC)

CAS No. : [945966-46-1]

Synonyms : MT-3995

IUPAC Name : N-(4-(4-Fluorophenyl)-2,2-dimethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl)methanesulfonamide

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Chemical Properites
Mol. Formula :
C17H17FN2O4S
Mol. Weight :
364.39
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Apararenone is a non‑steroidal antagonist of the mineralocorticoid receptor in clinical development for diabetic nephropathy and NASH. Its pharmacological profile positions it as a candidate for modulating inflammation, fibrosis, and metabolic dysfunction.

References : Kolkhof P. et al.: J. Endocrinol., 234(1), T125-T140, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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