Apitolisib

SI-1786

Apitolisib, 98% (HPLC)

CAS No. : [1032754-93-0]

MDL No. : MFCD20274520

Synonyms : GDC-0980; GNE 390; RG 7422

IUPAC Name : (R)-1-(4-((2-(2-Aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	75.00		Back Order	Estimated to ship on 04 October 2026
10MG	95.00		Back Order	Estimated to ship on 04 October 2026
25MG	125.00		Back Order	Estimated to ship on 04 October 2026
50MG	295.00		Back Order	Estimated to ship on 04 October 2026
100MG	495.00		Back Order	Estimated to ship on 04 October 2026
250MG	995.00		Back Order	Estimated to ship on 04 October 2026

Applications : Apitolisib is a selective, potent, orally bioavailable Class I PI3 kinase and mTOR kinase (TORC1/2) inhibitor with IC₅₀s of 5 nM/27 nM/7 nM/14 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ, and with a Ki of 17 nM for mTOR.

References : Sutherlin D. P. et al.: J. Med. Chem., 54(21), 7579-7587, 2011; Wallin J. J. et al.: Mol Cancer Ther., 10(12), 2426-2436,2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.